As the therapeutic approach toward degenerative diseases has so far been inadequate, an enormous medical need still remains unmet. Our technology has proven highly effective in the most reputed animal models of critical human diseases and is therefore mandatory now to ascertain whether its efficacy is confirmed in clinical studies. On the other hand, Negermin also presents excellent safety profile; in fact, although it was extensively searched and thoroughly assessed, Negermin so far never expressed any sign of toxicity, perhaps the most important cause of failure in the development of investigational drugs.

Our synthetic neurotrophin mimetics are primarily proposed for the treatment of: