MimeTech

Michele Tanturli

Michele Tanturli

Biostatistician and Data Management

Born in Firenze, Italy, 1983.

  • MD in Medical Biotechnologies, University of Firenze;
  • PhD in Clinical and Experimental Oncology, University of Firenze;
  • 1st Level Master in Biostatistics for Clinical Research and Scientific Reporting, University of Padova.

Since 2012 he is a staff scientist at MimeTech, where he gained extensive knowledge of statistics applied to clinical trials, clinical trial design, and regulatory practices.

His activity is mainly focused on the study of hypoxia and oxidative stress in ischemic and neurodegenerative diseases.

Publications

  1. Giuntoli S, Tanturli M, Di Gesualdo F, Barbetti V, Rovida E, Dello Sbarba P. Glucose availability in hypoxia regulates the selection of chronic myeloid leukemia progenitor subsets with different resistance to imatinib-mesylate. Haematologica. 2011 Feb;96(2):204-12. doi: 10.3324/haematol.2010.029082. Epub 2010 Nov 11. PubMed PMID: 21071498; PubMed Central PMCID: PMC3031687.
  2. Tanturli M, Giuntoli S, Barbetti V, Rovida E, Dello Sbarba P. Hypoxia selects bortezomib-resistant stem cells of chronic myeloid leukemia. PLoS One. 2011 Feb 11;6(2):e17008. doi: 10.1371/journal.pone.0017008. PubMed PMID: 21347297; PubMed Central PMCID: PMC3037943.
  3. Clemente AM, Severini C, Castronovo G, Tanturli M, Perissi E, Cozzolino F, Torcia MG. Effects of soluble extracts from Leishmania infantum promastigotes, Toxoplasma gondii tachyzoites on TGF-β mediated pathways in activated CD4+ T lymphocytes. Microbes Infect. 2014 Sep;16(9):778-87. doi: 10.1016/j.micinf.2014.08.002. Epub 2014 Aug 12. PubMed PMID: 25130316.
  4. Cheloni G, Tanturli M. The Culture Repopulation Ability (CRA) Assay and Incubation in Low Oxygen to Test Antileukemic Drugs on Imatinib-Resistant CML Stem-Like Cells. Methods Mol Biol. 2016;1465:73-85. doi: 10.1007/978-1-4939-4011-0_7. PubMed PMID: 27581140.
  5. Castronovo G, Clemente AM, Antonelli A, D’Andrea MM, Tanturli M, Perissi E, Paccosi S, Parenti A, Cozzolino F, Rossolini GM, Torcia MG. Differences in Inflammatory Response Induced by Two Representatives of Clades of the Pandemic ST258 Klebsiella pneumoniae Clonal Lineage Producing KPC-Type Carbapenemases. PLoS One. 2017 Jan 12;12(1):e0170125. doi: 10.1371/journal.pone.0170125. eCollection 2017. PubMed PMID: 28081233; PubMed Central PMCID: PMC5231394.
  6. Cheloni G, Tanturli M, Tusa I, Ho DeSouza N, Shan Y, Gozzini A, Mazurier F, Rovida E, Li S, Dello Sbarba P. Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine. Blood. 2017 Aug 3;130(5):655-665. doi: 10.1182/blood-2016-10-745588. Epub 2017 Jun 2. PubMed PMID: 28576876; PubMed Central PMCID: PMC5942867.
  7. Clemente AM, Castronovo G, Antonelli A, D’Andrea MM, Tanturli M, Perissi E, Paccosi S, Parenti A, Cozzolino F, Rossolini GM, Torcia MG. Differential Th17 response induced by the two clades of the pandemic ST258 Klebsiella pneumoniae clonal lineages producing KPC-type carbapenemase. PLoS One. 2017 Jun 6;12(6):e0178847. doi: 10.1371/journal.pone.0178847. eCollection 2017. PubMed PMID: 28586386; PubMed Central PMCID: PMC5460819.
  8. Di Paola M, Sani C, Clemente AM, Iossa A, Perissi E, Castronovo G, Tanturli M, Rivero D, Cozzolino F, Cavalieri D, Carozzi F, De Filippo C, Torcia MG. Characterization of cervico-vaginal microbiota in women developing persistent high-risk Human Papillomavirus infection. Sci Rep. 2017 Aug 31;7(1):10200. doi: 10.1038/s41598-017-09842-6. PubMed PMID: 28860468; PubMed Central PMCID: PMC5579045.
  9. Zakrzewska K, Arvia R, Torcia MG, Clemente AM, Tanturli M, Castronovo G, Sighinolfi G, Giuggioli D, Ferri C. Effects of Parvovirus B19 In Vitro Infection on Monocytes from Patients with Systemic Sclerosis: Enhanced Inflammatory Pathways by Caspase-1 Activation and Cytokine Production. J Invest Dermatol. 2019 Oct;139(10):2125-2133.e1. doi: 10.1016/j.jid.2019.03.1144. Epub 2019 Apr 9. PubMed PMID: 30978354.