Our synthetic neurotrophin mimetics are intended for treatment of corneal lesions, either spontaneous – the neurotrophic keratitis – or traumatic, or even iatrogenic, as is the case for laser treatment of miopy. In this connection, on 16/12/2014, our lead compound was designated as orphan drug for the treatment of neurotrophic …
Acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow in the coronary artery branch stops or is markedly reduced, causing damage to a part of the heart muscle. The mechanism may involve the complete blockage of a coronary artery, often caused by a rupture of an atherosclerotic …
Our synthetic neurotrophin mimetics may be used for treatment of diseases in which a defective trophic condition is involved in the pathogenesis, such as very important ilnesses of the Central Nervous System, like Amyotrophic Lateral Sclerosis and Parkinson’s Disease.
Pressure ulcers, also known as pressure sores, bedsores, and decubitus ulcers, are localized injuries to the skin and/or underlying tissue that usually occur over a bony prominence, as a result of pressure, or pressure in combination with shear and/or friction. The most common sites are the skin overlying the sacrum, coccyx, heels or the …
Solid organs destined to transplantation undergo ischemic damage as soon as they are explanted and then during their storage period. An additional injure, due to reperfusion, supervenes at the moment of their re-implant in the recipient. This medical field is, therefore, one of the most representative conditions of the Ischemia/Reperfusion (I/R) damage, …
Rare diseases under evaluation Amyotrophic lateral sclerosis Synonym(s) Charcot disease, Lou Gehrig disease ORPHA378 ICD-10 G12.2 UMLS C1527336 MedDRA 10040767 Status Under evaluation Retinitis Pigmentosa ORPHA791 ICD-10 H35.5 UMLS C0035334 MedDRA 10038914 Status Under evaluation
