Rare diseases under evaluation Amyotrophic lateral sclerosis Synonym(s) Charcot disease, Lou Gehrig disease ORPHA378 ICD-10 G12.2 UMLS C1527336 MedDRA 10040767 Status Under evaluation Retinitis Pigmentosa ORPHA791 ICD-10 H35.5 UMLS C0035334 MedDRA 10038914 Status Under evaluation
Recordati today announced that the FDA has granted Orphan Drug Designation to Recordati Rare Disease’s investigational product REC 0559 for the treatment of neurotrophic keratitis. REC 0559 is a low molecular weight non-peptidic human nerve growth factor (NGF) mimetic currently under global development by Recordati. REC 0559 was licensed in …
Recordati announced the signing of an exclusive license agreement with MimeTech for the development and subsequent commercialization on a global basis of a low molecular weight peptidomimetic of human nerve growth factor (NGF) for the treatment of neurotrophic keratitis, which already received an Orphan Drug Designation in the EU. Additional …
On 16/12/2014, orphan designation (EU/3/14/1400) was granted by the European Commission to MIMETECH S.r.l., Italy, for (1S,4R,5R,7S)-3,4-dibenzyl-2-oxo-6,8-dioxa-3-azabyciclo[3.2.1]octane-7-carboxylic acid-L-lysine for the treatment of neurotrophic keratitis. Patients with neurotrophic keratitis have lower than normal levels of growth factors that are normally supplied by the trigeminal nerve and which play an important role …
Neurotrophic Keratitis Synonym(s) Neurotrophic keratopathy ORPHA137596 ICD-10 H16.2 UMLS C0339296 MedDRA 10069732 Status In accordance with Regulation (EC) No 141/2000 of 16 December 1999, the Committee for Orphan Medicinal Products (COMP) adopted a positive opinion on 13 November 2014 recommending the granting of this designation. What is neurotrophic keratitis? Neurotrophic keratitis is a condition of …
