Degree in Medicine at the University of Rome “La Sapienza”, 1966.
His research activity mainly focused on virus-host cell interactions and immune defense mechanisms against tumors, viruses, and microorganisms.
He has been Dean of the University of Rome “Tor Vergata” from 1982 to 1993. He has been President of the National Research Council of Italy from 1993 to 1997. He has been President of the Superior Institute of Health from 2001 to 2013. He has been President of the Superior Health Council from 2009 to 2014.
He is now Dean of the Telematic University of Rome “San Raffaele”.